iOX – Infinite Oxygen Formulations™ flagship product, SustainO²gine™, was created in 2010 by founder, formulator and CEO John Mavros. Initially crafted with the intention of helping his wife fight her battle with Fibromyalgia, John’s revolutionary iOX supplement formula, SustainO²gine™, was quickly embraced by health experts to assist athletes, hard-working parents, and business professionals in doing what they do best, on a daily basis. Since developing SustainO²gine™, having it reviewed by many experts within the Health & Wellness Industry and then introducing it to the masses, SustainO²gine™ has not only helped John’s wife but has gone on to help thousands of individuals with their physical-mental endurance, energy production, exercise recovery, and overall immune strength.  John says “You will breathe easy knowing more will be accomplished in your day.”

Product Launch and Line Expansion:

With over 30 years in the Health & Sports Supplement Industry, John has accumulated hands-on knowledge that’s fueled him to create his unique supplement lines, including the iOX supplement collection. Once seeing SustainO²gine™ produce amazing results for his wife during its infancy, John began to introduce his supplements to other professionals within the industry, as well as athletes looking to improve their performance both on and off the field. The product performed so well that veterans with 20+ years of experience within the Health & Wellness Industry were ecstatic and gladly volunteered rave reviews. With the outpour of support, John was encouraged to expand his supplement line, and thus ProdaptO²gine™ and EPO²gine™ were created.

Our Mission:

Our mission is to bring you the most tested and effective multidimensional sport and life supplements ever created. Our various products are proudly utilized by pharmacists, doctors, first responders, professional athletes, hard-working parents, Tough Mudder athletes, and YES, our military. Thank you for your service! Whether you are an active mom, UFC Fighter, or musician on tour, we want your body working to the best of its ability so you can perform your greatest passions and duties in life. It does not matter if you’re in school, out of school, working hard at the office, or into extreme sports- each product in our supplement line helps your body’s engine run smoothly in their own unique ways.

About our Pharmaceutical Manufacturing Lab


cGMP refers to the Current Good Manufacturing Practice regulations enforced by the US Food and Drug Administration (FDA). 21 CFR 111: cGMP in Manufacturing, Packaging, Labeling, or Holding Operations for Dietary Supplements are the regulations requiring systems that assure proper design, monitoring, and control of manufacturing processes, packaging processes and facilities. Adherence to the cGMP regulations assures dietary supplements meet established specifications for identity, purity, strength, composition, and do not exceed their limits for contaminants.

Our Pharmaceutical Manufacturer is dedicated to producing dietary supplements of the highest quality. To help fulfill this mission we voluntarily maintain certifications and registrations with industry-leading organizations. Our Pharmaceutical Manufacturing lab holds and maintains the following certifications.

Our Manufacturer’s History

Two Decades Leading in Dietary Supplement Manufacturing

For over 20 years, our Pharmaceutical Manufacturing Lab, founded in New York in 1995, has become successful in the health and wellness supplementation market by leading the industry in full-service health supplement manufacturing. Everything is done in house – from product manufacturing to product testing, packaging and labeling – and is backed by our Pharmaceutical manufacturing lab’s guarantee of the highest in quality standards of compliance. Our facility is cGMP certified and FDA registered, for the manufacturing of dietary supplements.

iOX2’s Pharmaceutical Manufacturing Labs Advantage

Consistency, quality and complete customer satisfaction is our advantage. For over two decades our Pharmaceutical Manufacturer has been a leader in nutraceutical and dietary supplement manufacturing. Our commitment to our customers, science-based formulations, state of the art laboratories with the most comprehensive testing, production capabilities and vast inventory of on-demand raw materials helps us offer some of the most innovative products. Our manufacturing site is held to the highest standards and we are a cGMP certified and FDA registered facility.